Targeting of an activated T-cell subset using a bispecific antibody- toxin conjugate directed against CD4 and CD26
نویسندگان
چکیده
منابع مشابه
Targeting of an activated T-cell subset using a bispecific antibody-toxin conjugate directed against CD4 and CD26.
We have developed a bispecific antibody that recognizes the CD4 and CD26 antigens simultaneously and that was examined for its ability to target CD4+CD26+T cells. These latter cells constitute the activated component of the CD4+ CD29highCD45RO+ memory T-cell subset that provides help for B-cell Ig synthesis and help for responses against recall antigens. The purified bispecific antibody exhibit...
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ژورنال
عنوان ژورنال: Blood
سال: 1993
ISSN: 0006-4971,1528-0020
DOI: 10.1182/blood.v82.7.2224.2224